Genomics and Virulence of Fonsecaea pugnacius, Agent of Disseminated Chromoblastomycosis
نویسندگان
چکیده
منابع مشابه
Fonsecaea pugnacius, a Novel Agent of Disseminated Chromoblastomycosis.
We report a fatal case of a chromoblastomycosis-like infection caused by a novel species of Fonsecaea in a 52-year-old immunocompetent Caucasian male from an area of chromoblastomycosis endemicity in Brazil. The patient had a 30-year history of slowly evolving, verrucous lesions on the right upper arm which gradually affected the entire arm, the left hemifacial area, and the nose. Subsequent di...
متن کاملChromoblastomycosis Caused by Fonsecaea pedrosoi
We report herein a case of chromoblastomycosis caused by Fonsecaea (F.) pedrosoi in a 39-year-old male, who showed multiple, asymptomatic, scaly erythematous plaques on the left shin for 12 months. Histopathologically, chronic granulomatous inflammation and either sclerotic or muriform cells were observed. The fungal culture produced typical black colonies of F. pedrosoi. The DNA sequence of th...
متن کاملComparative Genomics of Sibling Species of Fonsecaea Associated with Human Chromoblastomycosis
Fonsecaea and Cladophialophora are genera of black yeast-like fungi harboring agents of a mutilating implantation disease in humans, along with strictly environmental species. The current hypothesis suggests that those species reside in somewhat adverse microhabitats, and pathogenic siblings share virulence factors enabling survival in mammal tissue after coincidental inoculation driven by path...
متن کاملCorneal Chromoblastomycosis Caused by Fonsecaea pedrosoi
PURPOSE To report 2 unusual cases of fungal keratitis due to Fonsecaea pedrosoi. METHODS Two patients were diagnosed with Fonsecaea pedrosoi keratitis. Their files were reviewed for predisposing factors, clinical characteristics, microbiological study, treatment, and outcome. RESULTS Two consecutive patients presented with brownish pigmented corneal ulcers in their eyes after sustaining eye...
متن کاملDraft Genome Sequence of Fonsecaea nubica Strain CBS 269.64, Causative Agent of Human Chromoblastomycosis
On the basis of multilocus phylogenetic data, Fonsecaea nubica was described in 2010 as a molecular sibling of F. monophora, an established agent of the human skin disease chomoblastomycosis in tropical zones. Genome analysis of these pathogens is mandatory to identify genes involved in the interaction with host and virulence.
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ژورنال
عنوان ژورنال: Frontiers in Genetics
سال: 2020
ISSN: 1664-8021
DOI: 10.3389/fgene.2020.00822